What type of genetic inheritance appears predominantly in males, with females usually being carriers?

The type of genetic inheritance that predominantly affects males, with females often serving as carriers, is X-linked recessive inheritance. This pattern occurs because males have one X and one Y chromosome, while females have two X chromosomes.

For a male to express an X-linked recessive trait, he needs only one copy of the recessive allele, as he is hemizygous for the X chromosome. In contrast, a female would need two copies of the recessive allele (one on each of her X chromosomes) to express the trait. Because females have two X chromosomes, they can be carriers if they have one normal allele and one recessive allele. They typically do not show symptoms of the trait since the normal allele can mask the effects of the recessive one.

This genetic inheritance pattern is seen in several conditions, such as color blindness and hemophilia, where affected males can transmit the allele to their daughters, who will be carriers but not usually show the condition themselves. Males cannot be carriers for X-linked traits; they either express the trait or do not, reinforcing the idea that X-linked recessive conditions are more apparent in males.

In contrast, the other options represent inheritance patterns that either do not show the same sex bias or